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HPLC study of the pharmacokinetics of K-203

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F08%3A00001930" target="_blank" >RIV/60162694:G44__/08:00001930 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    HPLC study of the pharmacokinetics of K-203

  • Original language description

    The pharmacokinetics of K-203, a recently synthesized bis-pyridinium aldoxime, have been investigated by reversed-phase HPLC. The K-203 content of serum samples was monitored by HPLC with ultraviolet absorbance detection at 286 nm. The low concentrationof K-203 in samples of brain, eyes, and cerebrospinal fluid was also determined by HPLC; quantitative evaluation was possible by use of an amperometric detector.

  • Czech name

    HPLC studie farmakokinetiky látky K-203

  • Czech description

    Farmakokinetika látky K203 - v současnosti syntetizovaného bispyridiniového oximu - byla zkoumána pomocí RP-HPLC. K203 obsah sérových vzorků bylo monitorováno pomocí HPLC-UV při 286 nm. Nízká koncentrace K203 ve vzorcích mozku, očí a cerebrospinální tekutiny byly rovněž určeny. Kvantitativní zhodnocení bylo umožněno amperometrickým detektorem.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FP - Other medical fields

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GP305%2F07%2FP162" target="_blank" >GP305/07/P162: Relationship between structure of acetylcholinesterase reactivators and their reactivation potency</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2008

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Acta Chromatographica

  • ISSN

    1233-2356

  • e-ISSN

  • Volume of the periodical

    20

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    PL - POLAND

  • Number of pages

    10

  • Pages from-to

  • UT code for WoS article

  • EID of the result in the Scopus database