Pharmacological prophylaxis against nerve agent poisoning: experimental studies and practical implications

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F09%3A00002117" target="_blank" >RIV/60162694:G44__/09:00002117 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Pharmacological prophylaxis against nerve agent poisoning: experimental studies and practical implications

Original language description

Pharmacological prophylaxis against nerve agentss and organophosphates is described. Approaches can be different: it is protection of acetylcholinesterase against inhibition when reversíble cholinesterase inhibitors are used (pyridostigmine). Its higherdose has side effect that can be eliminated by administration of anticholinergics (prophylactic antidote PANPAL). The treatment in advance comprises administration of reactivator HI-6 (TRANSANT). Administration of scavengers (cholinesterases, Protexia) decreases the level of toxic agent. The use of other drugs (huperzin A) is another possibility.

Czech name

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Czech description

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Type

C - Chapter in a specialist book

CEP classification

FP - Other medical fields

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Book/collection name

Handbook of toxicology of chemical warfare agents

ISBN

978-0-12-374484-5

Number of pages of the result

10

Pages from-to

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Number of pages of the book

1168

Publisher name

Acad Press Elsevier Sci

Place of publication

San Diego

UT code for WoS chapter

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