Innate immune NK celss and their role in HIV and SIV infection

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F10%3A00002245" target="_blank" >RIV/60162694:G44__/10:00002245 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Innate immune NK celss and their role in HIV and SIV infection
Original language description
The findings that early events during HIV-1and SIV infection of Asian macaques dictate the levels of viremia and rate of disease progression prior to the establishment of mature and effective adaptive imine responses strongly suggest en important role for ikate imine mechanisms. In addition, the fact that the major target of HIV and Siv during this period of acute infection is the gastrointestinal tissue suggests that whatever role the ikate imine systém plays must ether directly and/or indirectly focusonon the GI tract. The studies summarized include our current understanding of the phenotypic heterogenity, the stative functions ascribed to the subsets, the maturation/differentiation of NK cells, the mechanisms by which thein fiction is mediated and regulated, the studies these NK-cell subsets, which a focus on killer cell imunoglobulin like receptors (KIRs) in nonhuman primates and humus, how HIV and SIV infection affects these NK cell in vivo
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EC - Immunology
OECD FORD branch
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Project
<a href="/en/project/GAP304%2F10%2F1161" target="_blank" >GAP304/10/1161: Role of virus-associated host-derived proteins in virus induced T cell dysfunction</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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