The disulfide bond formation and its relationship to bacterial pathogenicity of three important Gram-negative bacteria

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F11%3A00002558" target="_blank" >RIV/60162694:G44__/11:00002558 - isvavai.cz</a>

Result on the web

<a href="http://www.vojenskaskola.cz/school/ud/fmhs/research_development/Documents/MMSL_2011_3_4_WWW.pdf" target="_blank" >http://www.vojenskaskola.cz/school/ud/fmhs/research_development/Documents/MMSL_2011_3_4_WWW.pdf</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

The disulfide bond formation and its relationship to bacterial pathogenicity of three important Gram-negative bacteria

Original language description

Disulfide bond formation is necessary for a correct folding and a proper function of many secreted proteins. We know that many of these proteins are involved in bacterial virulence and pathogenesis. The best known pathways of disulfide bond formation andisomerization belong to Escherichia coli (E. coli). This Gram-negative bacterium is usually used as a model organism. This review is focused firstly on introduction to E. coli oxido-reductase enzymatic system. The next part is interested in proteins resembling these from E. coli and their relation to virulence and pathogenesis. We have choosen three important Gram-negative pathogens, Neisseria meningitidis (N. meningitidis), Yersinia pestis (Y. pestis) and Francisella tularensis (F. tularensis), because of their high virulence, infectivity, ability to cause severe infections and absence of appropriate vaccines.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Military Medical Science Letters

ISSN

0372-7025

e-ISSN

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Volume of the periodical

80

Issue of the periodical within the volume

3

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

11

Pages from-to

118-128

UT code for WoS article

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EID of the result in the Scopus database

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