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The role of B cells in intracellular bacterial pathogen infections

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F13%3A43874904" target="_blank" >RIV/60162694:G44__/13:43874904 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.novapublishers.com/catalog/product_info.php?cPath=23_131_162&products_id=39506" target="_blank" >https://www.novapublishers.com/catalog/product_info.php?cPath=23_131_162&products_id=39506</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    The role of B cells in intracellular bacterial pathogen infections

  • Original language description

    The protective immune response against facultative intracellular bacterial pathogens, as are Brucella melitensis, Francisella tularensis, Listeria monocytogenes, or Salmonella sp. requires concerted action of activated immunocompetent cells. In this respect the dominant role has been attributed to activated T lymphocyte subpopulations and/or activated macrophages. Recently become clear that the B cell subsets are the equivalent partner of T cells during the induction, regulation and expression phases ofthe immune response against intracellular bacteria. They express their functions by both antibody-dependent and by antibody-independent mechanisms. B cells are able to internalize bacteria through their BCR, extract the antigens from the non-internalizable particles, and are able due to the cross-presentation process activate CD4+ as well as CD8+ T cells. Through the dichotomy of the recognition of bacterial targets by BCR or TLR and by the production of sets of cytokines the B cells re

  • Czech name

  • Czech description

Classification

  • Type

    C - Chapter in a specialist book

  • CEP classification

    EC - Immunology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GAP302%2F11%2F1631" target="_blank" >GAP302/11/1631: The role of B cells during natural and adaptive phase of immune response against Francisella tularensis infection in mice</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Book/collection name

    B Cells: Molecular Biology, Developmental Origin and Impact on the Immune System

  • ISBN

    978-1-62808-541-9

  • Number of pages of the result

    44

  • Pages from-to

    1-44

  • Number of pages of the book

    119

  • Publisher name

    Nova Science Publishers - NY

  • Place of publication

    New York

  • UT code for WoS chapter