The role of B cells in intracellular bacterial pathogen infections
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F13%3A43874904" target="_blank" >RIV/60162694:G44__/13:43874904 - isvavai.cz</a>
Result on the web
<a href="https://www.novapublishers.com/catalog/product_info.php?cPath=23_131_162&products_id=39506" target="_blank" >https://www.novapublishers.com/catalog/product_info.php?cPath=23_131_162&products_id=39506</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
The role of B cells in intracellular bacterial pathogen infections
Original language description
The protective immune response against facultative intracellular bacterial pathogens, as are Brucella melitensis, Francisella tularensis, Listeria monocytogenes, or Salmonella sp. requires concerted action of activated immunocompetent cells. In this respect the dominant role has been attributed to activated T lymphocyte subpopulations and/or activated macrophages. Recently become clear that the B cell subsets are the equivalent partner of T cells during the induction, regulation and expression phases ofthe immune response against intracellular bacteria. They express their functions by both antibody-dependent and by antibody-independent mechanisms. B cells are able to internalize bacteria through their BCR, extract the antigens from the non-internalizable particles, and are able due to the cross-presentation process activate CD4+ as well as CD8+ T cells. Through the dichotomy of the recognition of bacterial targets by BCR or TLR and by the production of sets of cytokines the B cells re
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
EC - Immunology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GAP302%2F11%2F1631" target="_blank" >GAP302/11/1631: The role of B cells during natural and adaptive phase of immune response against Francisella tularensis infection in mice</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
B Cells: Molecular Biology, Developmental Origin and Impact on the Immune System
ISBN
978-1-62808-541-9
Number of pages of the result
44
Pages from-to
1-44
Number of pages of the book
119
Publisher name
Nova Science Publishers - NY
Place of publication
New York
UT code for WoS chapter
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