Role of oxidative stress in infectious diseases. A review

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F13%3A43874961" target="_blank" >RIV/60162694:G44__/13:43874961 - isvavai.cz</a>
Result on the web
<a href="http://link.springer.com/article/10.1007%2Fs12223-013-0239-5" target="_blank" >http://link.springer.com/article/10.1007%2Fs12223-013-0239-5</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s12223-013-0239-5" target="_blank" >10.1007/s12223-013-0239-5</a>

Result language
angličtina
Original language name
Role of oxidative stress in infectious diseases. A review
Original language description
Oxidative stress plays a dual role in infections. Free radicals protect against invading microorganisms, and they can also cause tissue damage during the resulting inflammation. In the process of infection, there is generation of reactive species by myeloperoxidase, NADPH oxidase, and nitric oxide synthase. On the other hand, reactive species can be generated among others, by cytochrome P450, some metals, and xanthine oxidase. Some pathologies arising during infection can be attributed to oxidative stress and generation of reactive species in infection can even have fatal consequences. This article reviews the basic pathways in which reactive species can accumulate during infectious diseases and discusses the related health consequences.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Project
<a href="/en/project/LH11023" target="_blank" >LH11023: Improvement of vaccination efficacy by cholinergic anti-inflammatory pathway</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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