Evaluation of cytokines and soluble adhesion molecules in patients with newly diagnosed acute myeloid leukemia: the role of TNF-alpha and FLT3-ITD
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F16%3A43875448" target="_blank" >RIV/60162694:G44__/16:43875448 - isvavai.cz</a>
Alternative codes found
RIV/62690094:18450/16:50003865 RIV/00216208:11150/16:10317251 RIV/00179906:_____/16:10317251
Result on the web
<a href="http://biomed.papers.upol.cz/corproof.php?tartkey=bio-000000-1133" target="_blank" >http://biomed.papers.upol.cz/corproof.php?tartkey=bio-000000-1133</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5507/bp.2015.036" target="_blank" >10.5507/bp.2015.036</a>
Alternative languages
Result language
angličtina
Original language name
Evaluation of cytokines and soluble adhesion molecules in patients with newly diagnosed acute myeloid leukemia: the role of TNF-alpha and FLT3-ITD
Original language description
This study evaluates baseline serum levels of 16 cytokines and 4 soluble adhesion molecules in 53 patients treated for AML. We evaluated changes associated with age, secondary AML origin, hyperleukocytosis, failure of induction therapy and FLT3-ITD mutation status. Cytokine and adhesion molecule levels were not influenced by age. Patients with secondary AML were older than those with primary disease. The principal component was influenced by leukocyte count, FLT3-ITD mutation status and secondary origin of AML. In presence of FLT3-ITD mutation the E-selectin was higher and IL-7 lower. Adhesion molecule expression was activated as a whole, shoving probable links to endothelial cell activation.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biomedical Papers
ISSN
1213-8118
e-ISSN
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Volume of the periodical
160
Issue of the periodical within the volume
1
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
6
Pages from-to
94-99
UT code for WoS article
000373390800011
EID of the result in the Scopus database
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