Phone camera detection of glucose blood level based on magnetic particles entrapped inside bubble wrap

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F16%3A43875673" target="_blank" >RIV/60162694:G44__/16:43875673 - isvavai.cz</a>

Result on the web

<a href="http://www.nel.edu/Current_issue_0.htm" target="_blank" >http://www.nel.edu/Current_issue_0.htm</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Phone camera detection of glucose blood level based on magnetic particles entrapped inside bubble wrap

Original language description

OBJECTIVES: Glucose is an important diagnostic biochemical marker of diabetes but also for organophosphates, carbamates, acetaminophens or salicylates poisoning. Hence, innovation of accurate and fast detection assay is still one of priorities in biomedical research. METHODS: Glucose sensor based on magnetic particles (MPs) with immobilized enzymes glucose oxidase (GOx) and horseradish peroxidase (HRP) was developed and the GOx catalyzed reaction was visualized by a smart-phone-integrated camera. RESULTS: Exponential decay concentration curve with correlation coefficient 0.997 and with limit of detection 0.4 mmol/l was achieved. Interfering and matrix substances were measured due to possibility of assay influencing and no effect of the tested substances was observed. Spiked plasma samples were also measured and no influence of plasma matrix on the assay was proved. CONCLUSIONS: The presented assay showed complying results with reference method (standard spectrophotometry based on enzymes glucose oxidase and peroxidase inside plastic cuvettes) with linear dependence and correlation coefficient 0.999 in concentration range between 0 and 4 mmol/l. On the grounds of measured results, method was considered as highly specific, accurate and fast assay for detection of glucose.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10406 - Analytical chemistry

Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Neuroendocrinology Letters

ISSN

0172-780X

e-ISSN

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Volume of the periodical

37

Issue of the periodical within the volume

Suppl. 1

Country of publishing house

SE - SWEDEN

Number of pages

7

Pages from-to

132-138

UT code for WoS article

000406112100020

EID of the result in the Scopus database

2-s2.0-85018820388