Use of a new pneumatic system to support capillary microperfusion in surgical wound healing: an animal model

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F19%3A00541689" target="_blank" >RIV/60162694:G44__/19:00541689 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11150/19:10398637 RIV/00179906:_____/19:10398637

Result on the web

<a href="https://www.magonlinelibrary.com/toc/jowc/28/4" target="_blank" >https://www.magonlinelibrary.com/toc/jowc/28/4</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.12968/jowc.2019.28.4.229" target="_blank" >10.12968/jowc.2019.28.4.229</a>

Result language

angličtina

Original language name

Use of a new pneumatic system to support capillary microperfusion in surgical wound healing: an animal model

Original language description

Objective: To test the efficacy of the a developed medical device, based on the principle of mechanical support of capillary microperfusion. Method: In this pilot study involving experimental animals, each pig had two standardised surgical wounds. A cuff that delivered pneumatic three-second micropulses was applied to the wound designated as the 'experimental wound'. The pressure inside the cuff was kept at a level <10mmHg so that during the pulse, the pressure would decrease by one third of the established value. The second wound, designated as the 'control wound', was covered with a standard dressing. Over the course of five days, the pressure inside the cuff was monitored. After the five days, the experimental animal was euthanised and two specimens were collected for histological analysis (one sample from each wound site). Wound healing parameters for the experimental and control wounds were examined by a pathologist. The level of statistical significance was set at 0.05. Results: In this study, 10 experimental animals were used. The average pressure in the cuffs was 8.46mmHg (standard deviation: 3.86). No disparities in wound healing were observed in cases of different average pressures in the experimental wound. With respect to wound healing parameters, a statistically significant difference (p<0.05) was found in favour of the experimental wound. The occurrence of histological signs of poor healing was identical in both study wounds. Conclusion: The study shows that a device for the support of capillary microperfusion of the surgical wound had a positive effect. It was confirmed that the mechanical support system of capillary microperfusion was safe and reliable. Declaration of interest: The study received financial support from the institutional grant agency of the University Hospital Hradec Kralove. The authors have no conflicts of interest to declare.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30216 - Dermatology and venereal diseases

Project

—

Continuities

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Wound Care

ISSN

0969-0700

e-ISSN

2052-2916

Volume of the periodical

28

Issue of the periodical within the volume

4

Country of publishing house

GB - UNITED KINGDOM

Number of pages

9

Pages from-to

229-237

UT code for WoS article

000463574700007

EID of the result in the Scopus database

2-s2.0-85064282122