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The effect of hyperbaric oxygen therapy on acute wound healing in rabbits: An experimental study and histopathological analysis

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F21%3A43921325" target="_blank" >RIV/00216208:11120/21:43921325 - isvavai.cz</a>

  • Alternative codes found

    RIV/60162694:G44__/21:00556854

  • Result on the web

    <a href="https://doi.org/10.31482/mmsl.2021.001" target="_blank" >https://doi.org/10.31482/mmsl.2021.001</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.31482/mmsl.2021.001" target="_blank" >10.31482/mmsl.2021.001</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The effect of hyperbaric oxygen therapy on acute wound healing in rabbits: An experimental study and histopathological analysis

  • Original language description

    Background: The goal of our research is to show the effects and impacts of hyperbaric oxygen therapy (HBOT) on acute model wounds in animal subjects. Methods: Three experimental groups were created using injured rabbits (N=36)-randomly divided into three groups (N=12 per group). One group was treated only with standard wound care management. Two groups were additionally treated with HBOT either once or twice a day. The wounds were surgical, uninfected, and in healthy animal test subjects. We compared the immunohistochemical and histological parameters in 4-, 7-and 10-day intervals. Results: The detection of epidermal leaf parameters, the number of microabscesses, the Histopathological Superficial Epithelium Healing Score, Connective Tissue Healing Score, Histopathological Acute Inflammation Score and Total Histopathological Wound Healing Score all showed significant changes between time intervals within the individual groups. Conclusion: The results did not show that HBOT had a significant effect on the healing process of uncomplicated acute wounds.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database

  • CEP classification

  • OECD FORD branch

    30305 - Occupational health

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Vojenské zdravotnické listy / Military Medical Science Letters

  • ISSN

    0372-7025

  • e-ISSN

  • Volume of the periodical

    90

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    10

  • Pages from-to

    2-11

  • UT code for WoS article

  • EID of the result in the Scopus database

    2-s2.0-85102836855