D-Lactic Acid as a Metabolite: Toxicology, Diagnosis, and Detection

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F20%3A00555937" target="_blank" >RIV/60162694:G44__/20:00555937 - isvavai.cz</a>
Result on the web
<a href="http://www.hindawi.com/journals/biomed/" target="_blank" >http://www.hindawi.com/journals/biomed/</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2020/3419034" target="_blank" >10.1155/2020/3419034</a>

Result language
angličtina
Original language name
D-Lactic Acid as a Metabolite: Toxicology, Diagnosis, and Detection
Original language description
Two enantiomers of lactic acid exist. While L-lactic acid is a common compound of human metabolism, D-lactic acid is produced by some strains of microorganism or by some less relevant metabolic pathways. While L-lactic acid is an endogenous compound, D-lactic acid is a harmful enantiomer. Exposure to D-lactic acid can happen by various ways including contaminated food and beverages and by microbiota during some pathological states like short bowel syndrome. The exposure to D-lactic acid cannot be diagnosed because the common analytical methods are not suitable for distinguishing between the two enantiomers. In this review, pathways for D-lactic acid, pathological processes, and diagnostical and analytical methods are introduced followed by figures and tables. The current literature is summarized and discussed.
Czech name
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Czech description
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Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
20801 - Environmental biotechnology

Project
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Continuities
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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