ANALYSIS OF NERVE AGENTS THROUGH A MODIFIED METHOD OF CHOLINESTERASE ASSESSMENT USING ARTIFICIAL NEURONAL NETWORKS

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG45__%2F17%3A00534326" target="_blank" >RIV/60162694:G45__/17:00534326 - isvavai.cz</a>

Result on the web

<a href="https://www.mmsl.cz/pdfs/mms/2017/03/02.pdf" target="_blank" >https://www.mmsl.cz/pdfs/mms/2017/03/02.pdf</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

ANALYSIS OF NERVE AGENTS THROUGH A MODIFIED METHOD OF CHOLINESTERASE ASSESSMENT USING ARTIFICIAL NEURONAL NETWORKS

Original language description

A simple colorimetric biosensor, which uses the modified Ellman's reaction, enables selective analysis of nerve agents based on a different ability of bispyridinium oximes to reactivate enzyme-inhibitor complexes in the phase before dealkylation. The analysis was made based on spectral data of reflectance of the surface of a cotton cloth reaction zone of biosensor with immobilized and stabilized enzyme after inhibition and subsequent reactivation. The evaluation of measured data was made based on a method of artificial neuronal networks. The individual inhibitors from the groups of three nerve agents were identified: sarin, soman,tabun, cyclosarin, agent VX and its Russian analogue, R-33.

Czech name

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Czech description

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Type

J_ost - Miscellaneous article in a specialist periodical

CEP classification

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OECD FORD branch

50902 - Social sciences, interdisciplinary

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Military Medical Science Letters

ISSN

0372-7025

e-ISSN

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Volume of the periodical

86

Issue of the periodical within the volume

3

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

8

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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