Development of a method for the derivatization of ethanolamines and its application to sand samples
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG45__%2F23%3A00557038" target="_blank" >RIV/60162694:G45__/23:00557038 - isvavai.cz</a>
Result on the web
<a href="https://www.shd-pub.org.rs/index.php/JSCS/article/view/10507" target="_blank" >https://www.shd-pub.org.rs/index.php/JSCS/article/view/10507</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2298/JSC210312047R" target="_blank" >10.2298/JSC210312047R</a>
Alternative languages
Result language
angličtina
Original language name
Development of a method for the derivatization of ethanolamines and its application to sand samples
Original language description
Nitrogen mustards are dangerous and available blistering chemical warfare agents. In the presented study, six derivatization methods are compared for the analysis of degradation products of the most important blistering nitrogen mustards (ethyl diethanolamine, methyl diethanolamine and triethanolamine) by gas chromatography coupled with mass spectrometry. Five silylation methods (using BSTFA and BSA) and one trifluoroacetylation method (using TFAA) were tested. The derivatization reactions were performed in acetonitrile. As the method with optimal results, trifluoroacetylation by TFAA was selected. Analytes reacted with the corresponding reagent rapidly, quantitatively, with stable kinetics and at room temperature. Calibration curves for quantitative analysis of ethanolamines after TFAA derivatization were created. The corresponding detection limits varied between 9x10(-3) and 7x10(-5) mmol.dm(-3) for the tested analytes. The developed method was applied for the analysis of ethanolamines after extraction from sand using acetonitrile. Limits of detection were 11.4 to 12.3 mu g of the analyte in 1 g of sand. The use of the developed method in military deployable laboratories designated for the rapid identification of chemical warfare agents and corresponding degradation products is encouraged.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10400 - Chemical sciences
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
JOURNAL OF THE SERBIAN CHEMICAL SOCIETY
ISSN
0352-5139
e-ISSN
1820-7421
Volume of the periodical
87
Issue of the periodical within the volume
2
Country of publishing house
RS - THE REPUBLIC OF SERBIA
Number of pages
13
Pages from-to
233-245
UT code for WoS article
000719807500001
EID of the result in the Scopus database
2-s2.0-85126696839