Changes of proteins induced by arrested development (hypobiosis) in Trichostrongylus colubriformis

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F02%3A00003693" target="_blank" >RIV/60460709:41210/02:00003693 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Changes of proteins induced by arrested development (hypobiosis) in Trichostrongylus colubriformis
Original language description
The infective larvae were induced by hypobiosis triggering factors which included low temperature (5°C) and decreasing photoperiods, for 5 weeks. The appearance of variatons in the protein profile of Trichostrongylus colubriformis (Giles, 1892) was evaluated by means of SDS-PAGE and densitometric analysis. Important quantitative variations were identified in the protein levels of the induced larvae, where the amount of two polypeptides (molecular weight 200-220 kDa) decreased in range 32,3-35,4% and theamount of six polypeptides (molecular weight 20-28 kDa) increased in range 20,0-27,0% compared to the control sample. Control of hypobiosis was effected by inoculation to two groups of gerbils (Meriones unguiculatus). The first group was infected by co nditoned larvae and the second group was control. Rate of inhibited larvae of group with conditioned larvae was in range 55-100%, in control group with unconditioned larvae was rate of inhibited larvae 0 - 14%. This work demonstrated chang
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EG - Zoology
OECD FORD branch
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Publication year
2002
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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