Role of ryanodine and inositol triphosphate receptors in NO-dependent partthenogenetic activation of pig oocytes

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F05%3A11525" target="_blank" >RIV/60460709:41210/05:11525 - isvavai.cz</a>

Result on the web

—

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

Role of ryanodine and inositol triphosphate receptors in NO-dependent partthenogenetic activation of pig oocytes

Original language description

Porcine oocytes are in vitro conditions parthenogenetically actived (70%) after the treatment with 2mM NO-donor SNAP for 10 hours. The blockage of inositol triphosphate receptors has no effect on the activation of oocytes ba NO-donor. On the other hand,the blockers of ryanodine receptors procaine and ruthenium red blocked the activation of the oocytes induced by NO donor. These data indicate that the activation of pig oocytes with NO-donor is calcium-dependent. For the mobilization of intracellular calcium stores, the ryanodine receptors but not inositol triphosphate receptors play a key role.

Czech name

Úloha ryanodinových a inositol trifosfátových receptorů při NO-dependentní partenogenetické aktivaci prasečích oocytů

Czech description

Porcine oocytes are in vitro conditions parthenogenetically actived (70%) after the treatment with 2mM NO-donor SNAP for 10 hours. The blockage of inositol triphosphate receptors has no effect on the activation of oocytes ba NO-donor. On the other hand,the blockers of ryanodine receptors procaine and ruthenium red blocked the activation of the oocytes induced by NO donor. These data indicate that the activation of pig oocytes with NO-donor is calcium-dependent. For the mobilization of intracellular calcium stores, the ryanodine receptors but not inositol triphosphate receptors play a key role.

Type

D - Article in proceedings

CEP classification

GG - Zootechnics

OECD FORD branch

—

Project

—

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2005

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

Current Problems of Breeding, Health, Growth and Production of Pigs

ISBN

80-85645-50-5

ISSN

—

e-ISSN

—

Number of pages

6

Pages from-to

269-274

Publisher name

Biologická fakulta

Place of publication

České Budějovice

Event location

České Budějovice

Event date

Feb 9, 2005

Type of event by nationality

WRD - Celosvětová akce

UT code for WoS article

—