Bean alpha-amylase inhibitor: A perspective transgene for plant biotechnology applications.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F05%3A11972" target="_blank" >RIV/60460709:41210/05:11972 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Bean alpha-amylase inhibitor: A perspective transgene for plant biotechnology applications.
Original language description
The α-amylase inhibitors (AIs) became a new tool for regulation of important pathological processes through the application of plant biotechnologies. First, the plant AIs represent promising biopesticides for the development of resistant GM crops. This strategy is safe for humans since AIs naturally occur in crops as defensive proteins targeted against the digestive amylases of insects. The second emerging field is a potential use of orally given AIs in medicine in suppressing postprandial glucoselevels of diabetic patients. In this work, we present an analysis of inhibitory selectivity of αAI-1 from common bean (Phaseolus vulgaris cv. Magna). The inhibitory potential of αAI-1 was screened with a panel of the digestive α-amylases from 30 species of insects, mites, gastropod, annelid worm, nematode and fungal phytopathogens with a focus on agricultural pests and important model species. Based on results of the in vitro analysis, the in vivo activity of the ingested
Czech name
Fazolový alfa-amylázový inhibitor: Perspektivní transgen pro rostlinné biotechnologické aplikace
Czech description
The α-amylase inhibitors (AIs) became a new tool for regulation of important pathological processes through the application of plant biotechnologies. First, the plant AIs represent promising biopesticides for the development of resistant GM crops. This strategy is safe for humans since AIs naturally occur in crops as defensive proteins targeted against the digestive amylases of insects. The second emerging field is a potential use of orally given AIs in medicine in suppressing postprandial glucoselevels of diabetic patients. In this work, we present an analysis of inhibitory selectivity of αAI-1 from common bean (Phaseolus vulgaris cv. Magna). The inhibitory potential of αAI-1 was screened with a panel of the digestive α-amylases from 30 species of insects, mites, gastropod, annelid worm, nematode and fungal phytopathogens with a focus on agricultural pests and important model species. Based on results of the in vitro analysis, the in vivo activity of the ingested
Classification
Type
D - Article in proceedings
CEP classification
GF - Diseases, pests, weeds and plant protection
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2005
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
From Laboratory to Business. Recent Advances in Plant Biotechnology. České Budějovice
ISBN
80-86778-16-9
ISSN
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e-ISSN
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Number of pages
1
Pages from-to
16-16
Publisher name
Institute of Plant Molecular Biology ASCR
Place of publication
České Budějovice
Event location
České Budějovice
Event date
Sep 12, 2005
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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