The role of nitric oxide in parthenogenetic activation of pig oocytes: A review

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F07%3A23405" target="_blank" >RIV/60460709:41210/07:23405 - isvavai.cz</a>

Alternative codes found

RIV/00027014:_____/07:#0000483

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

The role of nitric oxide in parthenogenetic activation of pig oocytes: A review

Original language description

Parthenogenetic activation of mammalian oocytes with the help of artificial stimuli is commonly applied in various reproductive biotechniques. e.g. cloning using nuclear transfer. For this reason, many studies focus on oocyte activation in vitro. Recently we have described activation of pig oocytes using nitric oxide. This activating stimulus is very specific in many aspects. However, it does not provide an adequate stimulus for parthenogenetic development. It was shown, that nitric oxide stimulates some signaling pathways which are inactive in conventional treatments for parthenogenetic activation, e.g. the cGMP-dependent signaling cascade. On the other hand, nitric oxide does not stimulate some signaling pathways involved in oocyte activation after calcium ionophore, e.g. the PKC signaling cascade. The aim of this review is to characterize the complex processes induced in oocytes after treatment with nitric oxide. Perspectives for further research and the application of nitric oxide

Czech name

Úloha oxidu dusnatého při partenogenetické aktivaci prasečích oocytů - review

Czech description

Parthenogenetic activation of mammalian oocytes with the help of artificial stimuli is commonly applied in various reproductive biotechniques. e.g. cloning using nuclear transfer. For this reason, many studies focus on oocyte activation in vitro. Recently we have described activation of pig oocytes using nitric oxide. This activating stimulus is very specific in many aspects. However, it does not provide an adequate stimulus for parthenogenetic development. It was shown, that nitric oxide stimulates some signaling pathways which are inactive in conventional treatments for parthenogenetic activation, e.g. the cGMP-dependent signaling cascade. On the other hand, nitric oxide does not stimulate some signaling pathways involved in oocyte activation after calcium ionophore, e.g. the PKC signaling cascade. The aim of this review is to characterize the complex processes induced in oocytes after treatment with nitric oxide. Perspectives for further research and the application of nitric oxide

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

GG - Zootechnics

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2007

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Czech Journal of Animal Science

ISSN

1212-1819

e-ISSN

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Volume of the periodical

52

Issue of the periodical within the volume

11

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

15

Pages from-to

363-377

UT code for WoS article

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EID of the result in the Scopus database

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