Evaluation of DNA damage, toxicity and mutagenicity induced by lead in tobacco plants

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F08%3A24264" target="_blank" >RIV/60460709:41210/08:24264 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Evaluation of DNA damage, toxicity and mutagenicity induced by lead in tobacco plants

Original language description

Tobacco (Nicotiana tabacum L. var. xanthi) seedlings were treated with water solutions of lead nitrate (Pb2+) at concentrations ranging from 25 ?M to 2.4 mM for 24 h and 7 days. Pb content in the soil and in the plants was measured by inductively coupledplasma optical emission spectrometry. The DNA damage measured by the comet assay was high in the root nuclei, but in the leaf nuclei a slight but significant increase in DNA damage could be demonstrated only after day 7 with 200 ?M Pb2+ treatment. In tobacco plants growing for 6 weeks in soil polluted with Pb2+ severe toxic effects, expressed by the decrease in leaf area, and a slight but significant increase in DNA damage were observed. The tobacco plants with increased extent of DNA damage were severely injured exhibiting stunted growth, distorted leaves and brown root tips. This increase in DNA damage may be associated with necrotic or apoptotic DNA fragmentation. The frequency of somatic mutations in tobacco plants growing in the P

Czech name

Hodnocení stupně poškození DNA, toxicity a mutagenity vyvolané působením olova v rostlinách tabáku

Czech description

Tobacco (Nicotiana tabacum L. var. xanthi) seedlings were treated with water solutions of lead nitrate (Pb2+) at concentrations ranging from 25 ?M to 2.4 mM for 24 h and 7 days. Pb content in the soil and in the plants was measured by inductively coupledplasma optical emission spectrometry. The DNA damage measured by the comet assay was high in the root nuclei, but in the leaf nuclei a slight but significant increase in DNA damage could be demonstrated only after day 7 with 200 ?M Pb2+ treatment. In tobacco plants growing for 6 weeks in soil polluted with Pb2+ severe toxic effects, expressed by the decrease in leaf area, and a slight but significant increase in DNA damage were observed. The tobacco plants with increased extent of DNA damage were severely injured exhibiting stunted growth, distorted leaves and brown root tips. This increase in DNA damage may be associated with necrotic or apoptotic DNA fragmentation. The frequency of somatic mutations in tobacco plants growing in the P

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2008

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Mutation Research-Genetic Toxicology and Environmental Mutagenesis

ISSN

1383-5718

e-ISSN

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Volume of the periodical

652

Issue of the periodical within the volume

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Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

5

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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