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Calcineurin expression and localisation during porcine oocyte growth and meiotic maturation

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F13%3A61554" target="_blank" >RIV/60460709:41210/13:61554 - isvavai.cz</a>

  • Alternative codes found

    RIV/00027014:_____/13:#0001909

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Calcineurin expression and localisation during porcine oocyte growth and meiotic maturation

  • Original language description

    The processes of oocyte growth, acquisition of meiotic competence and meiotic maturation are regulated by a large number of molecules. One of them could be calcineurin consisting of catalytic subunit A (A-alpha, A-beta, A-gama isoforms) and regulatory subunit B (B1, B2 isoforms). Calcineurin is involved in the meiotic maturation of oocytes in invertebrates or in lower vertebrates. In the mammalian oocytes, the possible role of calcineurin in the regulation of oocyte meiosis has not been clarified to date. In this study, to investigate the role of calcineurin during porcine oocyte growth, acquisition of meiotic competence and meiotic maturation, we analysed the expression and localisation of calcineurin subunits and the mRNA expression of calcineurin isoforms. Calcineurin was expressed in growing porcine oocytes, in fully grown oocytes and during their in vitro meiotic maturation. We found both subunits of calcineurin. Calcineurin A and calcineurin B were localised mainly in the cortex

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    GG - Zootechnics

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GAP502%2F10%2F0794" target="_blank" >GAP502/10/0794: Acquisition of meiotic competence in pig oocytes - the effects of protein phosphatase calcineurin</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Animal Reproduction Science

  • ISSN

    0378-4320

  • e-ISSN

  • Volume of the periodical

    141

  • Issue of the periodical within the volume

    3-4

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    10

  • Pages from-to

    154-163

  • UT code for WoS article

    000326422300007

  • EID of the result in the Scopus database