The effect of risk factors of sheep flock management practices on the development of anthelmintic resistance in the Czech Republic

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F14%3A65513" target="_blank" >RIV/60460709:41210/14:65513 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
The effect of risk factors of sheep flock management practices on the development of anthelmintic resistance in the Czech Republic
Original language description
The in vivo faecal egg count reduction test was used for the evaluation of the benzimidazole and macrocylic lactone drug efficacies against gastrointestinal nematodes in 10 flocks of sheep. The same samples were tested concurrently in vitro for benzimidazole resistance using the egg hatch test, and for resistance to ivermectins using the microagar larval development test. The conformity of obtained results between in vivo and in vitro tests was recorded. When the selected methods were applied, anthelmintic resistance to benzimidazoles was detected at four (40%) farms while resistance to ivermectins was evident at one (10%) farm. At one farm (10%) ivermectin resistance was suspected. Moxidectin was effective at all surveyed farms. Teladorsagia was recognized as the only benzimidazole resistant genus in post-treatment coprocultures, whereas Haemonchus larvae were resistant to ivermectins. This represents the first recorded occurrence of ivermectin resistance in gastrointestinal nematodes
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
GJ - Diseases and animal vermin, veterinary medicine
OECD FORD branch
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Project
<a href="/en/project/QI111A199" target="_blank" >QI111A199: Efficient system in sheep breeding parasitosis prevention</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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