GARLIC SULFUR COMPOUNDS SUPPRESS CANCEROGENESIS AND OXIDATIVE STRESS: A REVIEW

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F15%3A67715" target="_blank" >RIV/60460709:41210/15:67715 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1515/sab-2015-0018" target="_blank" >http://dx.doi.org/10.1515/sab-2015-0018</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1515/sab-2015-0018" target="_blank" >10.1515/sab-2015-0018</a>

Result language

angličtina

Original language name

GARLIC SULFUR COMPOUNDS SUPPRESS CANCEROGENESIS AND OXIDATIVE STRESS: A REVIEW

Original language description

Garlic has long been considered a food with many health benefits. Several studies have confirmed that sulfur compounds are responsible for the positive effects of garlic on organisms. Garlic acts as an antioxidant by increasing antioxidant enzyme activity, reducing reactive oxygen species generation, and protecting proteins and lipids from oxidation. Garlic suppresses carcinogenesis through several mechanisms: (1) it reduces oxidative stress, and therefore, prevents damage to DNA; (2) it induces apoptosis or cell cycle arrest in cancer cells; and (3) it modifies gene expression through histon acetylation. The positive effects of garlic could be mediated by several mechanisms. It influences signalling pathways of gasotransmitters such as hydrogen sulfide. Garlic enhances hydrogen sulfide production both through its direct release and through an increase in activity of enzymes which produce hydrogen sulfide. Hydrogen sulfide acts as a signalling molecule in various tissues and participat

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

GI - Farm animal breeding and farm animal pedigree breeding

OECD FORD branch

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Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Scientia Agriculturae Bohemica

ISSN

1211-3174

e-ISSN

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Volume of the periodical

46

Issue of the periodical within the volume

2

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

8

Pages from-to

65-72

UT code for WoS article

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EID of the result in the Scopus database

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