Organo-sulphur garlic compounds influence viability of mammalian cells. A review.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F18%3A74027" target="_blank" >RIV/60460709:41210/18:74027 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.2478/sab-2018-0002" target="_blank" >http://dx.doi.org/10.2478/sab-2018-0002</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2478/sab-2018-0002" target="_blank" >10.2478/sab-2018-0002</a>
Alternative languages
Result language
angličtina
Original language name
Organo-sulphur garlic compounds influence viability of mammalian cells. A review.
Original language description
Garlic it is still in the centre of interest for its therapeutic effects. Currently, attention is focused on physiological effects of organo-sulphur garlic compounds, as alliin, allicin, diallyl sulfide (DAS), diallyl disulfide (DADS), diallyl trisulfide (DATS) and S-allyl cysteine (SAC), particularly on their antioxidant and anticancerogenic effects. SAC has been studied for its ability to decrease the production of reactive oxygen species by modulation of the cell glutathione level together with antioxidative enzyme activity, and by improvement of mitochondrial functions. The main mechanism of DAS, DADS, and DATS is induction of the internal apoptotic pathway. Garlic compounds have ability to interfere with the signalling pathways of small gaseous signalling molecules known as gasotransmitters, nitric oxide (NO), hydrogen sulphide (H2S) and carbon monoxide (CO). The review presents the effect of garlic compounds on cellular oxidative stress, intrinsic apoptotic, and gasotransmitter pathways and com
Czech name
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Czech description
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Classification
Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
30105 - Physiology (including cytology)
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Scientia Agriculturae Bohemica
ISSN
1211-3174
e-ISSN
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Volume of the periodical
49
Issue of the periodical within the volume
1
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
8
Pages from-to
9-16
UT code for WoS article
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EID of the result in the Scopus database
2-s2.0-85045880212