In vitro growth-inhibitory activity of Calophyllum inophyllum ethanol leaf extract against diarrhoea-causing bacteria

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F17%3A74149" target="_blank" >RIV/60460709:41210/17:74149 - isvavai.cz</a>

Alternative codes found

RIV/60460709:41340/17:74149

Result on the web

<a href="http://dx.doi.org/10.4314/tjpr.v16i9.23" target="_blank" >http://dx.doi.org/10.4314/tjpr.v16i9.23</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4314/tjpr.v16i9.23" target="_blank" >10.4314/tjpr.v16i9.23</a>

Result language

angličtina

Original language name

In vitro growth-inhibitory activity of Calophyllum inophyllum ethanol leaf extract against diarrhoea-causing bacteria

Original language description

Purpose: To investigate the in vitro growth-inhibitory effect of Calophyllum inophyllum, a medicinal plant traditionally used to cure gastrointestinal disorders caused by diarrhoea-causing bacteria. Methods: The minimum inhibitory concentration (MIC) of C. inophyllum ethanol leaf extract was determined against six diarrhoea-causing bacteria, namely, Clostridium difficile infant, Clostridium perfringens, Enterococcus faecalis, Escherichia coli, Listeria monocytogenes, and Salmonella enterica. The effect of the plant extract on bacterial growth kinetics was further evaluated by slightly modified broth microdilution method. Results: The plant extract showed significant inhibitory activity against C. perfringens and L. monocytogenes (MIC = 128 microg/mL) followed by C. difficile (MIC = 512 micro/mL). Monitored growth curves also showed that the plant extract at 0,5 MIC inhibits bacterial growth by distinct extension of the lag phase or suppression of the whole growth rate in C. difficile and L. monocytog

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

21101 - Food and beverages

Project

—

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH

ISSN

1596-5996

e-ISSN

—

Volume of the periodical

16

Issue of the periodical within the volume

9

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

7

Pages from-to

2207-2213

UT code for WoS article

000418444300022

EID of the result in the Scopus database

2-s2.0-85030546221