SIRT1-dependent modulation of methylation and acetylation of histone H3 on lysine 9 (H3K9) in the zygotic pronuclei improves porcine embryo development
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F17%3A74628" target="_blank" >RIV/60460709:41210/17:74628 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11140/17:10364033
Result on the web
<a href="http://dx.doi.org/10.1186/s40104-017-0214-0" target="_blank" >http://dx.doi.org/10.1186/s40104-017-0214-0</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/s40104-017-0214-0" target="_blank" >10.1186/s40104-017-0214-0</a>
Alternative languages
Result language
angličtina
Original language name
SIRT1-dependent modulation of methylation and acetylation of histone H3 on lysine 9 (H3K9) in the zygotic pronuclei improves porcine embryo development
Original language description
The histone code is an established epigenetic regulator of early embryonic development in mammals. The lysine residue K9 of histone H3 (H3K9) is a prime target of SIRT1, a member of NAD+dependent histone deacetylase family of enzymes targeting both histone and non-histone substrates. At present, little is known about SIRT1 modulation of H3K9 in zygotic pronuclei and its association with the success of preimplantation embryo development. Therefore, we evaluated the effect of SIRT1 activity on H3K9 methylation and acetylation in porcine zygotes and the significance of H3K9 modifications for early embryonic development.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Animal Science and Biotechnology
ISSN
2049-1891
e-ISSN
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Volume of the periodical
8
Issue of the periodical within the volume
N
Country of publishing house
GB - UNITED KINGDOM
Number of pages
12
Pages from-to
1-12
UT code for WoS article
000414592900001
EID of the result in the Scopus database
2-s2.0-85033389161