Screening of medicinal plants traditionally used in Peruvian Amazon for in vitro antioxidant and anticancer potential

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F18%3A76778" target="_blank" >RIV/60460709:41210/18:76778 - isvavai.cz</a>

Alternative codes found

RIV/60460709:41340/18:76778 RIV/60460709:41340/19:79954 RIV/60460709:41210/19:79954 RIV/60461373:22330/19:43917984

Result on the web

<a href="http://dx.doi.org/10.1080/14786419.2018.1462180" target="_blank" >http://dx.doi.org/10.1080/14786419.2018.1462180</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/14786419.2018.1462180" target="_blank" >10.1080/14786419.2018.1462180</a>

Result language

čeština

Original language name

Screening of medicinal plants traditionally used in Peruvian Amazon for in vitro antioxidant and anticancer potential

Original language description

Plants mentioned in this study have numerous records in traditional Peruvian medicine being used in treatment of cancer and other diseases likely to be associated with oxidative stress. Amongst the eight plant species tested, only Dysphania ambrosioides exhibited combinatory antioxidant and antiproliferative effect on a broad spectrum of cancer cells (DPPH and ORAC values = 80,6 and 687,3 ug TE/mg extract, respectively. IC50 against Caco-2, HT-29 and Hep-G2 = 129,2, 69,9 and 130,6, respectively). Alkaloids and phenolic compounds might significantly contribute to anticancer/antioxidant activity of this plant. The results justify the traditional medicinal use of this plant. Our findings further suggest that D. ambrosioides might serve as a prospective material for further development of novel plant-based antioxidant and/or antiproliferative agents. Detailed analysis of chemical composition together with toxicology assessments and in vivo antioxidant/antiproliferative activity of this plant should be ca

Czech name

Screening of medicinal plants traditionally used in Peruvian Amazon for in vitro antioxidant and anticancer potential

Czech description

Plants mentioned in this study have numerous records in traditional Peruvian medicine being used in treatment of cancer and other diseases likely to be associated with oxidative stress. Amongst the eight plant species tested, only Dysphania ambrosioides exhibited combinatory antioxidant and antiproliferative effect on a broad spectrum of cancer cells (DPPH and ORAC values = 80,6 and 687,3 ug TE/mg extract, respectively. IC50 against Caco-2, HT-29 and Hep-G2 = 129,2, 69,9 and 130,6, respectively). Alkaloids and phenolic compounds might significantly contribute to anticancer/antioxidant activity of this plant. The results justify the traditional medicinal use of this plant. Our findings further suggest that D. ambrosioides might serve as a prospective material for further development of novel plant-based antioxidant and/or antiproliferative agents. Detailed analysis of chemical composition together with toxicology assessments and in vivo antioxidant/antiproliferative activity of this plant should be ca

Type

J_SC - Article in a specialist periodical, which is included in the SCOPUS database

CEP classification

—

OECD FORD branch

30104 - Pharmacology and pharmacy

Project

—

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

NATURAL PRODUCT RESEARCH

ISSN

1478-6419

e-ISSN

1478-6427

Volume of the periodical

N

Issue of the periodical within the volume

14 Apr 2018

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

4

Pages from-to

1-4

UT code for WoS article

—

EID of the result in the Scopus database

2-s2.0-85045441418