Applicability of low-flow atmospheric pressure chemical ionization and photoionization mass spectrometry with a microfabricated nebulizer for neutral lipids

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F18%3A78619" target="_blank" >RIV/60460709:41210/18:78619 - isvavai.cz</a>

Alternative codes found

RIV/61388963:_____/18:00489841 RIV/00216208:11310/18:10374500

Result on the web

<a href="http://dx.doi.org/10.1002/rcm.8086" target="_blank" >http://dx.doi.org/10.1002/rcm.8086</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/rcm.8086" target="_blank" >10.1002/rcm.8086</a>

Result language

čeština

Original language name

Applicability of low-flow atmospheric pressure chemical ionization and photoionization mass spectrometry with a microfabricated nebulizer for neutral lipids

Original language description

Mass spectrometry with atmospheric pressure chemical ionization or photoionization is widely used for neutral lipids involved in many fundamental processes in living organisms. Commercial APCI and APPI sources operate at high flow rates compatible with conventional high-performance liquid chromatography. However, lipid analysis is often limited by a small amount of sample, which requires low flow rate separations like capillary or micro HPLC. Therefore, APCI and APPI suitable for microliter per minute flow rates need to be developed and applied for neutral lipids. Micro APCI or APPI source with a heated chip nebulizer was assembled and mounted on a Thermo ion trap instrument. The ion source operated in APCI, APPI or dual mode was optimized for low microliter per minute sample flow rates. The source performance was investigated for squalene, wax esters, fatty acid methyl esters, triacylglycerols, and cholesterol. The ion source behaved as a mass flow sensitive detector. Direct infusion of methyl oleat

Czech name

Applicability of low-flow atmospheric pressure chemical ionization and photoionization mass spectrometry with a microfabricated nebulizer for neutral lipids

Czech description

Mass spectrometry with atmospheric pressure chemical ionization or photoionization is widely used for neutral lipids involved in many fundamental processes in living organisms. Commercial APCI and APPI sources operate at high flow rates compatible with conventional high-performance liquid chromatography. However, lipid analysis is often limited by a small amount of sample, which requires low flow rate separations like capillary or micro HPLC. Therefore, APCI and APPI suitable for microliter per minute flow rates need to be developed and applied for neutral lipids. Micro APCI or APPI source with a heated chip nebulizer was assembled and mounted on a Thermo ion trap instrument. The ion source operated in APCI, APPI or dual mode was optimized for low microliter per minute sample flow rates. The source performance was investigated for squalene, wax esters, fatty acid methyl esters, triacylglycerols, and cholesterol. The ion source behaved as a mass flow sensitive detector. Direct infusion of methyl oleat

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10406 - Analytical chemistry

Project

<a href="/en/project/GA16-01639S" target="_blank" >GA16-01639S: Micro- and nanoflow atmospheric pressure ionizations for bioanalytical mass spectrometry</a><br>

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

RAPID COMMUNICATIONS IN MASS SPECTROMETRY

ISSN

0951-4198

e-ISSN

1097-0231

Volume of the periodical

32

Issue of the periodical within the volume

8

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

10

Pages from-to

639-648

UT code for WoS article

000428526800006

EID of the result in the Scopus database

2-s2.0-85044509116