Outstanding insecticidal activity and sublethal effects of Carlina acaulis root essential oil on the housefly, Musca domestica, with insights on its toxicity on human cells

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F20%3A82394" target="_blank" >RIV/60460709:41210/20:82394 - isvavai.cz</a>
Alternative codes found
RIV/00027006:_____/20:10149658
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0278691519308270?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0278691519308270?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.fct.2019.111037" target="_blank" >10.1016/j.fct.2019.111037</a>

Result language
angličtina
Original language name
Outstanding insecticidal activity and sublethal effects of Carlina acaulis root essential oil on the housefly, Musca domestica, with insights on its toxicity on human cells
Original language description
Carlina acaulis (Compositae) is traditionally used for food and medicinal purposes in central and southern Europe. Its root essential oil (EO), mainly composed by carlina oxide, is included in the BELFRIT botanical list of food supplements. It is also recognized as a potent mosquito larvicide. It is matter of concern whether this EO could be endowed with intrinsic toxicity to limit its use on a food level. Focusing on the insecticidal activity of this EO, we investigated the acute toxicity and sublethal effects on Musca domestica. In topical assays, the EO was extremely effective (LD50 = 2,74 and 5,96 mu g fly(-1), on males and females, respectively). The exposure to a sublethal dose (LD30) led to significant reductions of female longevity (LT50 = 6,7-9,0 days vs. control LT50 = 12,9-13,7 days). Treated females laid 2,5 times fewer eggs over control ones. F-1 vitality decreased: F-1 larvae and pupae showed high mortality, 2-4-fold higher over the control. The EO also showed high cytotoxicity on norma
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
40106 - Agronomy, plant breeding and plant protection; (Agricultural biotechnology to be 4.4)

Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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