Anti-staphylococcal activity, cytotoxicity, and chemical composition of hexane extracts from arils and seeds of two Samoan Myristica spp

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F21%3A88191" target="_blank" >RIV/60460709:41210/21:88191 - isvavai.cz</a>
Alternative codes found
RIV/60460709:41340/21:88191
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S025462992100017X" target="_blank" >https://www.sciencedirect.com/science/article/pii/S025462992100017X</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.sajb.2021.01.009" target="_blank" >10.1016/j.sajb.2021.01.009</a>

Result language
angličtina
Original language name
Anti-staphylococcal activity, cytotoxicity, and chemical composition of hexane extracts from arils and seeds of two Samoan Myristica spp
Original language description
Hexane extracts derived from the arils and seeds of two Samoan indigenous plant species, Myristica hypargyraea A. Gray and Myristica inutilis Rich ex A. Gray, were assessed for their in vitro anti-staphylococcal effect using a broth microdilution assay. Additionally, their cytotoxic activity against human colon cancer and normal intestinal cell lines was determined. In this study, all plant extracts tested showed a certain degree of growth-inhibitory effect against various strains of Staphylococcus aureus with minimum inhibitory concentrations (MICs) ranging from 8 to 1,024 g mL. The aril extract of M. hypargyraea possessed the highest antibacterial activity with MIC value 8 ug mL against one standard strain and three clinical isolates of S. aureus, the effective concentrations of this extract were found to be safe for the intestinal cells. The aril extract of M. inutilis showed the highest selective antiproliferative effect on intestinal cancer cells with a lower toxicity to normal cell lines. Usin
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10611 - Plant sciences, botany

Project
<a href="/en/project/EF16_019%2F0000845" target="_blank" >EF16_019/0000845: Centre for investigation of synthesis and transformation of nutritional substances in the food chain in interaction with potentially harmful substances of athropogenic origin: assessment of contamination risks for the quality of production</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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