Identification of the optimal codons for acetolactate synthase from weeds: an in-silico study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F21%3A88332" target="_blank" >RIV/60460709:41210/21:88332 - isvavai.cz</a>
Result on the web
<a href="https://www.agriculturejournals.cz/web/pse.htm?type=article&id=562_2020-PSE" target="_blank" >https://www.agriculturejournals.cz/web/pse.htm?type=article&id=562_2020-PSE</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.17221/562/2020-PSE" target="_blank" >10.17221/562/2020-PSE</a>
Alternative languages
Result language
angličtina
Original language name
Identification of the optimal codons for acetolactate synthase from weeds: an in-silico study
Original language description
Although various studies of codon usage bias have been reported in a broad spectrum of organisms, no studies to date have examined codon usage bias for herbicide target genes. In this study, we analysed codon usage patterns for the acetolactate synthase (ALS) gene in eight monocot weeds and one model monocot. Additionally, the optimal codons, along with over- and under-represented codons, were identified. Gene design using optimal codons rather than overall abundant codons produce improved protein expression results. Our results can be used for further studies, including eliciting the mechanisms of herbicide resistance (occurring due to elevation of gene expression levels) and the development of new compounds, their efficiency and risk assessment for herbicide resistance evolution.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
40106 - Agronomy, plant breeding and plant protection; (Agricultural biotechnology to be 4.4)
Result continuities
Project
<a href="/en/project/QK1820081" target="_blank" >QK1820081: Resistance monitoring methods of economically important pests and weeds to pesticides and anti-resistance strategies</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Plant, Soil and Environment
ISSN
1214-1178
e-ISSN
1805-9368
Volume of the periodical
67
Issue of the periodical within the volume
6
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
6
Pages from-to
331-336
UT code for WoS article
000653182000003
EID of the result in the Scopus database
2-s2.0-85107395783