Total Failure of Fenbendazole to Control Strongylid Infections in Czech Horse Operations
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F22%3A91812" target="_blank" >RIV/60460709:41210/22:91812 - isvavai.cz</a>
Result on the web
<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899116/" target="_blank" >https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899116/</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3389/fvets.2022.833204" target="_blank" >10.3389/fvets.2022.833204</a>
Alternative languages
Result language
angličtina
Original language name
Total Failure of Fenbendazole to Control Strongylid Infections in Czech Horse Operations
Original language description
The control of strongylid infections has become challenging globally for equine practitioners due to the development of anthelmintic resistance. Comprehensive information on anthelmintic resistance in the Czech Republic, however, is still lacking. This study monitored the current efficacy of fenbendazole, pyrantel embonate, ivermectin and moxidectin. Forty-eight of 71 operations met the criteria, with 969 fecal egg count reduction tests performed. Anthelmintic resistance was evaluated on an operation level based on fecal egg count reduction (FECR) and the lower limit of the 95% credible interval (LLCI) using Bayesian hierarchical models. General anthelmintic efficacy across all operations was assessed by posterior FECRs and the occurrence of sub-zero efficacies. Ivermectin and moxidectin demonstrated excellent efficacy in 45 and 23 operations, respectively, pyrantel embonate demonstrated sufficient efficacy in 15 operations and resistance was suspected in seven operations. Fenbendazole, however, was
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
40301 - Veterinary science
Result continuities
Project
<a href="/en/project/LTC19018" target="_blank" >LTC19018: Pilot strategic plan of combating against the resistant strains of parasitic worms in the populations of Czech farm ruminants</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Frontiers in Veterinary Sciences
ISSN
2297-1769
e-ISSN
2297-1769
Volume of the periodical
9
Issue of the periodical within the volume
February 2022
Country of publishing house
CH - SWITZERLAND
Number of pages
7
Pages from-to
0-0
UT code for WoS article
000796717100001
EID of the result in the Scopus database
2-s2.0-85125842977