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Low-density lipoprotein supplementation improves the quality of Holstein bulls' insemination doses

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F23%3A95184" target="_blank" >RIV/60460709:41210/23:95184 - isvavai.cz</a>

  • Result on the web

    <a href="https://doi.org/10.17221/223/2022-CJAS" target="_blank" >https://doi.org/10.17221/223/2022-CJAS</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.17221/223/2022-CJAS" target="_blank" >10.17221/223/2022-CJAS</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Low-density lipoprotein supplementation improves the quality of Holstein bulls' insemination doses

  • Original language description

    Despite the routine use of cryopreservation in dairy cattle, the subsequent deterioration in the quality of bull insemination doses (IDs) is an incentive to refine cryopreservation protocols, including the composition of the ID. The aim of this study was to examine, using a flow cytometry assay, whether the selected concentrations of low density lipoproteins (LDLs) extracted from hen-egg yolk may improve the post-thaw quality of the ID diluted with a plant-based extender. In total, 30 ejaculates from five sires (six trials per animal) were collected and processed at the Artificial Insemination Centre. The effect of the low density lipoprotein supplementation to the AndroMed (R) diluent at 4 and 8% (v/v) on the cryopreservation efficiency was tested. The effects of the modified extenders were determined on different sperm subpopulations by simultaneous quadruple staining for flow cytometry as the per-centage of sperm with intact plasma membrane and acrosome (PMAI), PMAI sperm showing high mitochondrial membrane potential (HMMP), sperm with plasma membrane damage (PMD), and sperm with acrosome damage (AD). It was observed that the 8% LDL treatment was more effective (P < 0.05) in preserving all the analysed param-eters than AndroMed (R) without any supplementation. The supplementation of the AndroMed (R) extender with 8% LDL resulted in the most optimal values of the PMAI (30.61 +/- 1.13), HMMP (68.81 +/- 1.25), PMD (68.69 +/- 1.14), and AD (38.36 +/- 1.13) compared to the control treatment (24.86 +/- 1.13 for PMAI, 47.79 +/- 1.25 for HMMP, 74.77 +/- 1.14 for PMD, and 42.83 +/- 1.13 for AD. The results of the study also demonstrated a synergistic positive effect of the LDL and soybean lecithin-based diluent on the spermatozoa post-thaw quality and resilience, based on 2 h long incubation. In conclusion, the soybean based semen extender treatment with LDL represents a beneficial tool to mitigate the detrimental effect of cryopreservation.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    40101 - Agriculture

Result continuities

  • Project

    <a href="/en/project/QK22010270" target="_blank" >QK22010270: Management optimalization of individual reproduction performance in dairy cattle</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Czech Journal of Animal Science

  • ISSN

    1212-1819

  • e-ISSN

    1212-1819

  • Volume of the periodical

    68

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    8

  • Pages from-to

    64-71

  • UT code for WoS article

    000950569800001

  • EID of the result in the Scopus database

    2-s2.0-85151400422