Origin of the Sao Paulo Yellow Fever Epidemic of 2017-2018 Revealed Through Molecular Epidemiological Analysis of Fatal Cases
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41340%2F19%3A81168" target="_blank" >RIV/60460709:41340/19:81168 - isvavai.cz</a>
Result on the web
<a href="https://www.nature.com/articles/s41598-019-56650-1" target="_blank" >https://www.nature.com/articles/s41598-019-56650-1</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41598-019-56650-1" target="_blank" >10.1038/s41598-019-56650-1</a>
Alternative languages
Result language
angličtina
Original language name
Origin of the Sao Paulo Yellow Fever Epidemic of 2017-2018 Revealed Through Molecular Epidemiological Analysis of Fatal Cases
Original language description
The largest outbreak of yellow fever of the 21st century in the Americas began in 2016, with intense circulation in the southeastern states of Brazil, particularly in sylvatic environments near densely populated areas including the metropolitan region of Sao Paulo city, MRSP, during 2017 and 2018. Herein, we describe the origin and molecular epidemiology of yellow fever virus, YFV, during this outbreak inferred from 36 full genome sequences taken from individuals who died following infection with zoonotic YFV. Our analysis revealed that these deaths were due to three genetic variants of sylvatic YFV that belong the South American I genotype and that were related to viruses previously isolated in 2017 from other locations in Brazil, Minas Gerais, Espirito Santo, Bahia and Rio de Janeiro states. Each variant represented an independent virus introduction into the MRSP. Phylogeographic and geopositioning analyses suggested that the virus moved around the peri urban area without detectable human to human
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10607 - Virology
Result continuities
Project
—
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Scientific Reports
ISSN
2045-2322
e-ISSN
2045-2322
Volume of the periodical
9
Issue of the periodical within the volume
1
Country of publishing house
GB - UNITED KINGDOM
Number of pages
10
Pages from-to
1-10
UT code for WoS article
000508985300039
EID of the result in the Scopus database
2-s2.0-85077209331