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Synthesis of (E)-6-Alkenylpurines via Pd-catalyzed Stannation protodestannation Tandem Process of Alkynylpurines.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F10%3A00023075" target="_blank" >RIV/60461373:22310/10:00023075 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Synthesis of (E)-6-Alkenylpurines via Pd-catalyzed Stannation protodestannation Tandem Process of Alkynylpurines.

  • Original language description

    A methodology for the synthesis of (E)-6-alkenylpurines, starting from 6-iodopurines, based on a Pd-catalyzed stannation/protodestannation protocol is described. The alkynylation reactions were catalyzed by Pd(OAc)2/PPh3 in acetonitrile. The Pd-catalyzedstannation itself provided a mixture of Z-regioisomers but following protodestannation using TFA induces Z to E isomerisation giving (E)-6-alkenylpurines. The reactivity of other 2- and 6-alkynyl purines has been also studied.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CC - Organic chemistry

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2010

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Collection of Czechoslovak Chemical Communications

  • ISSN

    0010-0765

  • e-ISSN

  • Volume of the periodical

    75

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    20

  • Pages from-to

  • UT code for WoS article

    000277125900006

  • EID of the result in the Scopus database