Palladium-catalysed Claisen rearrangement of 6-allyloxypurines

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F13%3A43894563" target="_blank" >RIV/60461373:22310/13:43894563 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22810/13:43894563
Result on the web
<a href="http://dx.doi.org/10.2478/s11696-012-0239-y" target="_blank" >http://dx.doi.org/10.2478/s11696-012-0239-y</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2478/s11696-012-0239-y" target="_blank" >10.2478/s11696-012-0239-y</a>

Result language
angličtina
Original language name
Palladium-catalysed Claisen rearrangement of 6-allyloxypurines
Original language description
6-Allyloxypurines readily undergo palladium-catalysed Claisen rearrangement under mild conditions affording N (1)-substituted hypoxanthines. In contrast with the previously reported protocol, the Claisen rearrangement can be performed using Pd(PPh3)(4) or Pd(dba)(2)/dppf in dry THF at 60A degrees C. The reaction can accommodate variously substituted allyl fragments to position N (1) of the hypoxanthine skeleton with high yields. Retention of the double bond configuration during rearrangement was observed.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
—

Project
<a href="/en/project/GA203%2F09%2F1552" target="_blank" >GA203/09/1552: Application of 7,8-Dihydropurines in the Synthesis of New Purine Derivatives with Potential Biological Activity</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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