Plasma treated polyethylene grafted with adhesive Molecules for enhanced adhesion and growth of fibroblasts
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F13%3A43895365" target="_blank" >RIV/60461373:22310/13:43895365 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22330/13:43895365
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S0928493112005607" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0928493112005607</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.msec.2012.12.003" target="_blank" >10.1016/j.msec.2012.12.003</a>
Alternative languages
Result language
angličtina
Original language name
Plasma treated polyethylene grafted with adhesive Molecules for enhanced adhesion and growth of fibroblasts
Original language description
The cell material interface plays a crucial role in the interaction of cells with synthetic materials for biomedical use. The application of plasma for tailoring polymer surfaces is of abiding interest and holds a great promise in biomedicine. In this paper, we describe polyethylene (PE) surface tuning by Ar plasma irradiating and subsequent grafting of the chemically active PE surface with adhesive proteins or motives to support cell attachment. These simple modifications resulted in changed polymer surface hydrophilicity, roughness and morphology, which we thoroughly characterized. The effect of our modifications on adhesion and growth was tested in vitro using mouse embryonic fibroblasts (NIH 3T3 cell line). We demonstrate that the plasma treatmentof PE had a positive effect on the adhesion, spreading, homogeneity of distribution and moderately on proliferation activity of NIH 3T3 cells. This effect was even more pronounced on PE coated with biomolecules.
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
JJ - Other materials
OECD FORD branch
—
Result continuities
Project
<a href="/en/project/GBP108%2F12%2FG108" target="_blank" >GBP108/12/G108: Preparation, modification and characterization of materials by radiation</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Materials science and engineering C
ISSN
0928-4931
e-ISSN
—
Volume of the periodical
33
Issue of the periodical within the volume
3
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
9
Pages from-to
1116-1124
UT code for WoS article
000315751600015
EID of the result in the Scopus database
—