Thickness and substrate dependences of phase transition, drug release and antibacterial properties of PNIPAm- co -AAc films

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F15%3A43900163" target="_blank" >RIV/60461373:22310/15:43900163 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22330/15:43900163
Result on the web
<a href="http://pubs.rsc.org/en/content/articlepdf/2015/ra/c5ra13972d?page=search" target="_blank" >http://pubs.rsc.org/en/content/articlepdf/2015/ra/c5ra13972d?page=search</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/c5ra13972d" target="_blank" >10.1039/c5ra13972d</a>

Result language
angličtina
Original language name
Thickness and substrate dependences of phase transition, drug release and antibacterial properties of PNIPAm- co -AAc films
Original language description
Micron and submicron poly(N-isopropylacrylamide)-co-(acrylic acid) (PNIPAm-co-AAc) films were deposited onto silicon and gold substrates by the spin-coating procedure. The in fluence of polymer-substrate interaction and spatial confinement of macromolecular chains in the ultrathin polymer films on lower critical solution temperature (LCST) was investigated under different pH conditions. Shift and broadening of the LCST temperature range was observed from the critical thickness of polymer film. It was also found that the substrate plays a key role in this shift. The observed phenomenon was applied for the temperature-controllable release of a small molecular dopant (crystal violet, CV) from the ultrathin polymer films. Finally, doped ultrathin polymer films were examined for their antibacterial activity by in-contact and drop methods. It was observed that polymer thickness and support substrate can influence both CV release and antibacterial properties. Despite the fact that the concent
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
JJ - Other materials
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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