PRINS CYCLIZATION OF ISOVALERALDEHYDE AND ISOPRENOL

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F15%3A43900228" target="_blank" >RIV/60461373:22310/15:43900228 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
PRINS CYCLIZATION OF ISOVALERALDEHYDE AND ISOPRENOL
Original language description
2-iso-Butyl-4-methyl-tetrahydro-2H-pyran-4-ol, also called Florosa or Florol, is commercially very attractive compound due to its fragrant properties. It is usually prepared by acid catalyzed Prins cyclization of isovaleraldehyde and isoprenol. The mechanism of Prins cyclization consists of, in the first step, the formation of hemiacetal (reaction of one molecule of aldehyde and alcohol), followed by cyclization of hemiacetal to cyclic carbocationic intermediate. Carbocationic intermediate is attacked by nucleophile from reaction media or catalyst, forming the product - tetrahydropyran-4-ol or undesired dihydropyranes. Separation of these products from reaction mixture is a very complicated process, so the leading of the reaction with very high selectivity is a crucial step in the reaction. In this work the different catalytic systems were tested for Prins cyclization - Bronsted and Lewis acid catalysts (both types in heterogeneous and homogeneous forms) and also the reaction condition
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Proceedings of the 3rd International Conference on Chemical Technology
ISBN
978-80-86238-79-1
ISSN
2336-811X
e-ISSN
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Number of pages
4
Pages from-to
27-30
Publisher name
Česká společnost průmyslové chemie (ČSPCH)
Place of publication
Praha
Event location
Mikulov
Event date
Apr 13, 2015
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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