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Multiscale modelling of DNA mechanics

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F15%3A43900545" target="_blank" >RIV/60461373:22310/15:43900545 - isvavai.cz</a>

  • Alternative codes found

    RIV/61388963:_____/15:00446777 RIV/00216208:11310/15:10315645

  • Result on the web

    <a href="http://dx.doi.org/10.1088/0953-8984/27/32/323102" target="_blank" >http://dx.doi.org/10.1088/0953-8984/27/32/323102</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1088/0953-8984/27/32/323102" target="_blank" >10.1088/0953-8984/27/32/323102</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Multiscale modelling of DNA mechanics

  • Original language description

    Mechanical properties of DNA are important not only in a wide range of biological processes but also in the emerging field of DNA nanotechnology. We review some of the recent developments in modeling these properties, emphasizing the multiscale nature of the problem. Modern atomic resolution, explicit solvent molecular dynamics simulations have contributed to our understanding of DNA fine structure and conformational polymorphism. These simulations may serve as data sources to parameterize rigid base models which themselves have undergone major development. A consistent buildup of larger entities involving multiple rigid bases enables us to describe DNA at more global scales. Free energy methods to impose large strains on DNA, as well as bead models and other approaches, are also briefly discussed.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CF - Physical chemistry and theoretical chemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA14-21893S" target="_blank" >GA14-21893S: Nanomechanics of RNA and DNA structural motifs</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    JOURNAL OF PHYSICS-CONDENSED MATTER

  • ISSN

    0953-8984

  • e-ISSN

  • Volume of the periodical

    27

  • Issue of the periodical within the volume

    22

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    12

  • Pages from-to

    323102

  • UT code for WoS article

    000358596400002

  • EID of the result in the Scopus database