High power plasma as an efficient tool for polymethylpentene cytocompatibility enhancement

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F16%3A43902212" target="_blank" >RIV/60461373:22310/16:43902212 - isvavai.cz</a>

Alternative codes found

RIV/61389005:_____/16:00463672

Result on the web

<a href="http://pubs.rsc.org/en/Content/ArticleLanding/2016/RA/C6RA14949A#!divAbstract" target="_blank" >http://pubs.rsc.org/en/Content/ArticleLanding/2016/RA/C6RA14949A#!divAbstract</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1039/c6ra14949a" target="_blank" >10.1039/c6ra14949a</a>

Result language

angličtina

Original language name

High power plasma as an efficient tool for polymethylpentene cytocompatibility enhancement

Original language description

High power plasma was successfully used as an efficient and inexpensive tool for polymethylpentene (PMP) cytocompatibility enhancement. Proper surface roughness and morphology as well as the surface chemistry of a material are essential factors for successful utilization of a substrate intended for tissue engineering applications. Plasma treatment is an inexpensive, simple and highly effective method for optimization of surface properties, as a result of which enhancement of cell adhesion, growth and migration occurs. Oxygen and argon plasma treatments were applied to activate the PMP surface. The research was focused on the investigation of the changed properties. The AFM and FIB-SEM study demonstrated that plasma treatments of PMP induced structured surfaces which depended on the applied plasma setting. Measurement of the goniometry, and chemical changes (functional groups by FTIR, element concentration by XPS and RBS/ERDA) was included. Experiments on treated substrates with mouse fibroblasts (NIH 3T3) have shown a significant increase in cell adhesion and proliferation on treated PMP substrates when compared to the untreated polymer. Similarly, cell morphology and adhesion sites were carefully examined using fluorescence and scanning electron microscopy; results of both techniques confirmed the suitability of treated PMP samples for cell cultivation. This study demonstrates how to easily improve cytocompatibility of a very inert and resistant polymer for tissue engineering applications.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

JJ - Other materials

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

RSC Advances

ISSN

2046-2069

e-ISSN

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Volume of the periodical

6

Issue of the periodical within the volume

79

Country of publishing house

GB - UNITED KINGDOM

Number of pages

11

Pages from-to

76000-76010

UT code for WoS article

000381513800117

EID of the result in the Scopus database

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