Smart metal nanostructures for effective bacterial inhibition
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F16%3A43902616" target="_blank" >RIV/60461373:22310/16:43902616 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Smart metal nanostructures for effective bacterial inhibition
Original language description
The increasing resistance of pathogenic bacteria to conventional antibiotics is a major problem of public health in the second half of this century. Therefore, it is exceptionally desired to search non-conventional antimicrobial agents able to inhibit microbial growth. This chapter provides comprehensive overview on smart materials based on structured noble metals covering its various forms from ultrathin layers over discrete metal islands up to isolated nanoparticles having exceptional properties applicable in prevention of bacterial infections. The type of underlaying substrate, forming the support for active metal nanostructure, was carefully chosen to match the specific application of individual composites (organic polymer fibers and layers, artificial polymer foils). Engineered antimicrobial materials are tested on vast range of microorganisms of Staphylococcus epidermidis, Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli. First subsection of the chapter is devoted to overview on antibacterial activity of Ag and Pd nanostructures prepared by DC sputtering on polymeric foils (PI, PEN) of great medical-care importance. The possibility of managing nanostructure size via controlling the thickness of metal nanolayers prior to their annealing is considered. Antibacterial properties of such metal/polymer composites are evaluated by a drip test using Gram-positive and Gram-negative bacteria. Significant differences between antibacterial response of Ag/PI and Pd/PEN is revealed. Secondly, the system of polymer/metal composites with triggerable activity is discussed and some examples of such systems are introduced. As external stimuli the pH, temperature or light is used to activate antimicrobial activity.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
JJ - Other materials
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Antibacterials: Synthesis, Properties and Biological Activities
ISBN
978-1-63485-793-2
Number of pages of the result
42
Pages from-to
27-68
Number of pages of the book
271
Publisher name
Nova Science Publishers, Inc.
Place of publication
New York
UT code for WoS chapter
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