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TITANIA NANOTUBULAR SURFACE TESTING

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F16%3A43903567" target="_blank" >RIV/60461373:22310/16:43903567 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    čeština

  • Original language name

    Testování nanostrukturovaných povrchů

  • Original language description

    Direct connection of the implant with bone could be long term and difficult process. Surface of the titanium and its alloys can be bioactivated by nanostructuring. The growth of nanotubes is result of two simultaneous processes. First of them is anodic oxidation of the surface and the second one is the local dissolution of the growing titanium dioxide by fluoride ions. Morphology of tubes can be influenced by appropriate electrolyte and anodic polarization parameters. Nanostructured surfaces stimulate the deposition of osteoblast cells, which leads to easier integration of the implant into the bone. This work was focused on the nanostructuing of the Ti-6Al-4V alloy and on the studying of the nanostructures properties. For morphological characterization of samples, scanning electron microscope was used. X-ray photoelectron spectroscopy (XPS) was used for the surface analysis. The adhesion of the nanotubes was tested by a pull-off method and by scratch test. The biological properties of the nanostructures were studied with osteoblast like cells. Finally, in vivo tests with pigs were done. Based on the tests results, the nanostructuring seems to be a very promising surface treatment for medical implants made from titanium alloys. This surface treatment was successfully realized on real implants.

  • Czech name

    Testování nanostrukturovaných povrchů

  • Czech description

    Direct connection of the implant with bone could be long term and difficult process. Surface of the titanium and its alloys can be bioactivated by nanostructuring. The growth of nanotubes is result of two simultaneous processes. First of them is anodic oxidation of the surface and the second one is the local dissolution of the growing titanium dioxide by fluoride ions. Morphology of tubes can be influenced by appropriate electrolyte and anodic polarization parameters. Nanostructured surfaces stimulate the deposition of osteoblast cells, which leads to easier integration of the implant into the bone. This work was focused on the nanostructuing of the Ti-6Al-4V alloy and on the studying of the nanostructures properties. For morphological characterization of samples, scanning electron microscope was used. X-ray photoelectron spectroscopy (XPS) was used for the surface analysis. The adhesion of the nanotubes was tested by a pull-off method and by scratch test. The biological properties of the nanostructures were studied with osteoblast like cells. Finally, in vivo tests with pigs were done. Based on the tests results, the nanostructuring seems to be a very promising surface treatment for medical implants made from titanium alloys. This surface treatment was successfully realized on real implants.

Classification

  • Type

    O - Miscellaneous

  • CEP classification

    JK - Corrosion and material surfaces

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/TE01020390" target="_blank" >TE01020390: Centre of the development of advanced metallic biomaterials for medical implants</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů