TITANIA NANOTUBULAR SURFACE TESTING
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F16%3A43903567" target="_blank" >RIV/60461373:22310/16:43903567 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
čeština
Original language name
Testování nanostrukturovaných povrchů
Original language description
Direct connection of the implant with bone could be long term and difficult process. Surface of the titanium and its alloys can be bioactivated by nanostructuring. The growth of nanotubes is result of two simultaneous processes. First of them is anodic oxidation of the surface and the second one is the local dissolution of the growing titanium dioxide by fluoride ions. Morphology of tubes can be influenced by appropriate electrolyte and anodic polarization parameters. Nanostructured surfaces stimulate the deposition of osteoblast cells, which leads to easier integration of the implant into the bone. This work was focused on the nanostructuing of the Ti-6Al-4V alloy and on the studying of the nanostructures properties. For morphological characterization of samples, scanning electron microscope was used. X-ray photoelectron spectroscopy (XPS) was used for the surface analysis. The adhesion of the nanotubes was tested by a pull-off method and by scratch test. The biological properties of the nanostructures were studied with osteoblast like cells. Finally, in vivo tests with pigs were done. Based on the tests results, the nanostructuring seems to be a very promising surface treatment for medical implants made from titanium alloys. This surface treatment was successfully realized on real implants.
Czech name
Testování nanostrukturovaných povrchů
Czech description
Direct connection of the implant with bone could be long term and difficult process. Surface of the titanium and its alloys can be bioactivated by nanostructuring. The growth of nanotubes is result of two simultaneous processes. First of them is anodic oxidation of the surface and the second one is the local dissolution of the growing titanium dioxide by fluoride ions. Morphology of tubes can be influenced by appropriate electrolyte and anodic polarization parameters. Nanostructured surfaces stimulate the deposition of osteoblast cells, which leads to easier integration of the implant into the bone. This work was focused on the nanostructuing of the Ti-6Al-4V alloy and on the studying of the nanostructures properties. For morphological characterization of samples, scanning electron microscope was used. X-ray photoelectron spectroscopy (XPS) was used for the surface analysis. The adhesion of the nanotubes was tested by a pull-off method and by scratch test. The biological properties of the nanostructures were studied with osteoblast like cells. Finally, in vivo tests with pigs were done. Based on the tests results, the nanostructuring seems to be a very promising surface treatment for medical implants made from titanium alloys. This surface treatment was successfully realized on real implants.
Classification
Type
O - Miscellaneous
CEP classification
JK - Corrosion and material surfaces
OECD FORD branch
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Result continuities
Project
<a href="/en/project/TE01020390" target="_blank" >TE01020390: Centre of the development of advanced metallic biomaterials for medical implants</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů