Surface changes of polymer modified by gold nanoparticles

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F17%3A43914103" target="_blank" >RIV/60461373:22310/17:43914103 - isvavai.cz</a>

Alternative codes found

RIV/60461373:22330/17:43914103

Result on the web

<a href="http://www.inderscience.com/storage/f386121074952111.pdf" target="_blank" >http://www.inderscience.com/storage/f386121074952111.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1504/IJNT.2017.082451" target="_blank" >10.1504/IJNT.2017.082451</a>

Result language

angličtina

Original language name

Surface changes of polymer modified by gold nanoparticles

Original language description

A limitation of polymers is that the materials lack active sites or substances that can promote cell adhesion, proliferation and tissue recovery. Biopolymers with functional groups or synthesised polymers modified with different methods show many potential applications. The way to create nanostructured surfaces with new functionalities is grafting of the nanoparticles to polymer surfaces. The different uptake behaviours for surface modified nanoparticles can be explained by different charges on the nanoparticles and on the cell membrane. In this work surface changes of the biopolymers substrate modified by gold nanoparticles were studied. Biopolymer foil of polyhydroxybutyrate with 8% polyhydroxyvalerate was treated by plasma and the activated surface was subsequently modified by gold nanoparticles. Modified substrates were analysed by different methods. The elemental composition and the structure of modified polyhydroxybutyrate with 8% polyhydroxyvalerate were studied by X-ray photoelectron spectroscopy (XPS). Surface morphology was determined using atomic force microscopy (AFM). Changes in the surface wettability were determined from the contact angle by goniometry. Cytocompatibility of the pristine and modified samples was assessed in vitro by determining degree of adhesion and proliferation of mouse fibroblasts. It was found that the plasma treatment and subsequent modification with gold nanoparticles leads to dramatic changes in surface morphology, roughness and wettability. Rate of changes of these features strongly depends on the modification parameters. Plasma treatment and subsequent grafting of nanoparticles significantly affects the adhesion and proliferation of cells on the surface of polymer. Biological experiments indicated favourable effect of the presence of the AuNS grafted from the citrate-stabilised AuNS solution on the cells&apos; adhesion, proliferation and viability.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

20501 - Materials engineering

Project

<a href="/en/project/GBP108%2F12%2FG108" target="_blank" >GBP108/12/G108: Preparation, modification and characterization of materials by radiation</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International Journal of Nanotechnology

ISSN

1475-7435

e-ISSN

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Volume of the periodical

14

Issue of the periodical within the volume

1-6

Country of publishing house

CH - SWITZERLAND

Number of pages

13

Pages from-to

120-132

UT code for WoS article

000396495300014

EID of the result in the Scopus database

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