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Micromotor-Assisted Human Serum Glucose Biosensing

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F19%3A43918338" target="_blank" >RIV/60461373:22310/19:43918338 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216305:26620/19:PU133192

  • Result on the web

    <a href="https://pubs.acs.org/doi/10.1021/acs.analchem.8b05464" target="_blank" >https://pubs.acs.org/doi/10.1021/acs.analchem.8b05464</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1021/acs.analchem.8b05464" target="_blank" >10.1021/acs.analchem.8b05464</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Micromotor-Assisted Human Serum Glucose Biosensing

  • Original language description

    Artificial self-propelled micromachines have shown great promise in biomedical sciences. In this work, we use Mg/Pt Janus micromotors with self-rejuvenating surfaces to enhance the electrochemical sensing performance and sensitivity toward glucose in human serum. The detection of glucose is based on the glucose oxidase enzyme and ferrocenemethanol shuttle system, where mass transfer was dramatically enhanced by the rapid motion of Mg/Pt Janus micromotors. The obtained chronoamperometric data show that Mg/Pt Janus micromotors play a synergistic role in enhancing the current response at millimolar concentrations of glucose in human serum. The current signals increased with the corresponding increase in amount of micro-motors introduced. Furthermore, a linear relationship between current signal and glucose concentration was established, while the limit of detection improved when mobile Mg/Pt Janus micromachines were used. Glucose detection enhanced by micromachines may pave the way for their future applications in biomedicine and medical diagnostic devices.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10406 - Analytical chemistry

Result continuities

  • Project

  • Continuities

    O - Projekt operacniho programu

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Analytical Chemistry

  • ISSN

    0003-2700

  • e-ISSN

  • Volume of the periodical

    91

  • Issue of the periodical within the volume

    9

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    7

  • Pages from-to

    5660-5666

  • UT code for WoS article

    000467642100030

  • EID of the result in the Scopus database

    2-s2.0-85064969484