Periodical amphiphilic surface with chemical patterning for micelles immobilization and analysis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F22%3A43924550" target="_blank" >RIV/60461373:22310/22:43924550 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22320/22:43924550
Result on the web
<a href="https://doi.org/10.1016/j.apsusc.2022.152833" target="_blank" >https://doi.org/10.1016/j.apsusc.2022.152833</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.apsusc.2022.152833" target="_blank" >10.1016/j.apsusc.2022.152833</a>
Alternative languages
Result language
angličtina
Original language name
Periodical amphiphilic surface with chemical patterning for micelles immobilization and analysis
Original language description
We present a strategy to produce periodically patterned surface with the controlled hydrophilic and hydrophobic nanoareas. The developed approach comprises colloid lithography using vapor-annealed polystyrene (PS) microspheres mask and two-step electrochemical surface grafting. The grafting was performed using the diazonium surface chemistry before and after colloid mask removal in order to introduce hydrophilic Ph-COOH and hydrophobic Ph-C8F17 moieties. Grafted chemical moities were covalently attached to the surface. The procedure results in creation of a surface with nanoprecisely located periodical hydrophobic and hydrophilic areas, with different sizes and geometry, determined by vapor annealing of PS microspheres. The created amphiphilic surface shows good biorepelency towards bovine serum albumin (BSA) and a high affinity towards amphiphilic micelles. Variation of surface nanoarchitecture elucidates the optimal surface chemistry for immobilization and surface entrapping of drug-loaded micelles. The formation of additional interface between amphilic surface and micelles was proved by dramatic decrease of the contact angle. According to Fourier-transform infrared spectroscopy (FTIR) results, created amphiphilic surfaces can capture drug-loaded micelles even in the presence of BSA biomatrix. Described procedure represents a versatile and scalable method for the creation of stable amphiphilic coating and its potential application in qualitative analysis and identification of micelles.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
20501 - Materials engineering
Result continuities
Project
<a href="/en/project/GJ19-24603Y" target="_blank" >GJ19-24603Y: Metal surface modification - new generation of icephobic materials</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Applied Surface Science
ISSN
0169-4332
e-ISSN
—
Volume of the periodical
586
Issue of the periodical within the volume
JUN 1 2022
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
10
Pages from-to
"152833/1"-10
UT code for WoS article
000774752900001
EID of the result in the Scopus database
—