New efficient catalysts based on hydrotalcite for synthesis of sandalwood-type fragrances

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F24%3A43928000" target="_blank" >RIV/60461373:22310/24:43928000 - isvavai.cz</a>

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S0920586123004297?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0920586123004297?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.cattod.2023.114405" target="_blank" >10.1016/j.cattod.2023.114405</a>

Result language

angličtina

Original language name

New efficient catalysts based on hydrotalcite for synthesis of sandalwood-type fragrances

Original language description

The presented study focuses on the development of metal-modified bifunctional catalysts based on hydrotalcites (HT) and their utilization for the „one-pot“ synthesis of 2-methyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)but-2-enol, also known as Santalinol. Such fragrance has a strong scent of sandalwood and is used in the perfume and cosmetics industry. The synthesis of Santalinol involves two steps: the aldol condensation of campholenic aldehyde with propanal to form 2-methyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)but-2-enal (santalinal), followed by selective hydrogenation. Three hydrotalcites with different magnesium-aluminium ratios ranging from 2 to 3 were prepared and tested for aldol condensation. Among them, the most active catalyst was modified with a metal using the impregnation method and various metal precursors. The modification using palladium (II) acetylacetonate solution in toluene proved to be the most advantageous. An efficient bifunctional catalyst was prepared, consisting of a hydrotalcite with a magnesium-aluminium ratio of 2.5 and 0.1 wt% of palladium for Santalinol synthesis. Under optimal conditions in a one-pot reaction, a 40% conversion of campholenic aldehyde was achieved after aldol condensation, with a selectivity of 86% towards santalinal. During the hydrogenation step, a selectivity of up to 75% towards Santalinol, relative to the formed santalinal, was observed. © 2023 Elsevier B.V.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10401 - Organic chemistry

Project

—

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

CATALYSIS TODAY

ISSN

0920-5861

e-ISSN

1873-4308

Volume of the periodical

427

Issue of the periodical within the volume

Neuveden

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

11

Pages from-to

nestránkováno

UT code for WoS article

001097144800001

EID of the result in the Scopus database

2-s2.0-85175053825