Modified Biosensor for Cholinesterase Inhibitors with Guinea Green B as the Color Indicator
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22320%2F18%3A43916239" target="_blank" >RIV/60461373:22320/18:43916239 - isvavai.cz</a>
Alternative codes found
RIV/68407700:21460/18:00324294 RIV/70565813:_____/18:N0000004
Result on the web
<a href="https://www.mdpi.com/2079-6374/8/3/81" target="_blank" >https://www.mdpi.com/2079-6374/8/3/81</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/bios8030081" target="_blank" >10.3390/bios8030081</a>
Alternative languages
Result language
angličtina
Original language name
Modified Biosensor for Cholinesterase Inhibitors with Guinea Green B as the Color Indicator
Original language description
Colorimetric biosensors of cholinesterase inhibitors are ideal for fast, reliable, and very simple detection of agents in air, in water, and on surfaces. This paper describes an innovation of the Czech Detehit biosensor, which is based on a biochemical enzymatic reaction visualized by using Ellman's reagent as a chromogenic indicator. The modification basically consists of a much more distinct color response of the biosensor, attained through optimization of the reaction system by using Guinea Green B as the indicator. The performance of the modified biosensor was verified on the chemical warfare agents (sarin, soman, cyclosarin, and VX) in water. The detection limits ascertained visually (with the naked eye) were about 0.001 µg/mL in water (exposure time 60 s, inhibition efficiency 25%).
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10401 - Organic chemistry
Result continuities
Project
<a href="/en/project/VI20152018024" target="_blank" >VI20152018024: NEW TECHNOLOGIES FOR PERSONAL DETECTOR OF CHOLINE ESTERASE INHIBITORS</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biosensors
ISSN
2079-6374
e-ISSN
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Volume of the periodical
8
Issue of the periodical within the volume
3
Country of publishing house
CH - SWITZERLAND
Number of pages
10
Pages from-to
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UT code for WoS article
000448396500025
EID of the result in the Scopus database
2-s2.0-85054766054