Structure and antitumour activity of fucoidan isolated from sporophyll of Korean brown seaweed Undaria pinnatida

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F10%3A00024311" target="_blank" >RIV/60461373:22330/10:00024311 - isvavai.cz</a>

Alternative codes found

RIV/61388963:_____/10:00352928

Result on the web

—

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

Structure and antitumour activity of fucoidan isolated from sporophyll of Korean brown seaweed Undaria pinnatida

Original language description

Fucoidan from the sporophyll (Miyeokgui) of cultured Korean brown seaweeds Undaria pinnatifida (Miyeok) is interesting due to its various biological activities. This polysaccharide was isolated from raw material by dilute acid extraction, ballast alginates were removed by CaCl2 precipitation, and crude extract was purified by chromatography on DEAE-cellulose. Structure and composition of the fucoidan was characterised by various methods (organic elemental analysis, HPLC analysis of neutral sugars, FTIR,FT-Raman, H-1 and C-13 NMR); molecular size and charge density were estimated by GPC and CITP. The polysaccharide was eluted by GPC as a single peak of approximate molecular weight of 1246 kDa. Miyeokgui fucoidan showed lower electrophoretic mobility (RSH similar to 0.127) than carrageenans (0.096-0.100) and chondroitin sulphate A (0.103) but higher than alginate (0.170). Isolated polysaccharide contained alpha-fucose (50.9 mol%) and beta-galactose (44.6 mol%) as main neutral sugar unit

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CB - Analytical chemistry, separation

OECD FORD branch

—

Project

—

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Carbohydrate Polymers

ISSN

0144-8617

e-ISSN

—

Volume of the periodical

81

Issue of the periodical within the volume

1

Country of publishing house

IE - IRELAND

Number of pages

8

Pages from-to

—

UT code for WoS article

000277953500007

EID of the result in the Scopus database

—