Mekabu fucoidan: Structural complexity and defensive effects against avian influenza A viruses

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F14%3A00431746" target="_blank" >RIV/61388963:_____/14:00431746 - isvavai.cz</a>

Alternative codes found

RIV/60461373:22330/14:43897082 RIV/60461373:22340/14:43897082

Result on the web

<a href="http://dx.doi.org/10.1016/j.carbpol.2014.05.032" target="_blank" >http://dx.doi.org/10.1016/j.carbpol.2014.05.032</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.carbpol.2014.05.032" target="_blank" >10.1016/j.carbpol.2014.05.032</a>

Result language

angličtina

Original language name

Mekabu fucoidan: Structural complexity and defensive effects against avian influenza A viruses

Original language description

Fucoidan from the sporophyll (Mekabu) of brown seaweed Undaria pinnatifida (wakame) is interesting due to its various biological activities. Mekabu fucoidan (M-w similar to 9 kDa) of this study (MF) was previously isolated and characterized by chemical and separation methods including GPC and methylation analysis (Lee, Hayashi, Hashimoto, Nakano, & Hayashi, 2004). It was found that this fucoidan composed of partially sulphated (DS similar to 0.72) fucose and galactose at approximately equal amounts. Methylation analyses revealed complex structure of MF. However, it has been still unclear about the linkages between units and substitution patterns. To solve these structural tasks, spectroscopic methods (FTIR, FT Raman and NMR) were used in the analysis of native MF and its deesterified derivatives. According to obtained results, this polysaccharide was defined as O-acetylated sulphated fucogalactan. The defensive effects of MF were evaluated on mice infected with avian influenza A viruse

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CC - Organic chemistry

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Carbohydrate Polymers

ISSN

0144-8617

e-ISSN

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Volume of the periodical

111

Issue of the periodical within the volume

Oct 13

Country of publishing house

GB - UNITED KINGDOM

Number of pages

12

Pages from-to

633-644

UT code for WoS article

000340302100077

EID of the result in the Scopus database

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