Antioxidative succinobucol-sterol conjugates: Crystal structures and pseudosymmetry in the crystals

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F12%3A43894012" target="_blank" >RIV/60461373:22330/12:43894012 - isvavai.cz</a>
Alternative codes found
RIV/61389030:_____/12:00380688
Result on the web
<a href="http://dx.doi.org/10.1016/j.molstruc.2011.12.016" target="_blank" >http://dx.doi.org/10.1016/j.molstruc.2011.12.016</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.molstruc.2011.12.016" target="_blank" >10.1016/j.molstruc.2011.12.016</a>

Result language
angličtina
Original language name
Antioxidative succinobucol-sterol conjugates: Crystal structures and pseudosymmetry in the crystals
Original language description
An extensive study to attach succinobucol to sterols has provided conjugates which comprise two pharmaceutically important compounds into one entity where the components are expected to have a synergistic effect. The motivation to design these novel conjugates was the need to broaden the armamentarium of current agents used in the treatment of atherosclerotic diseases and type 2 diabetes. In desire for detailed information of these compounds in solid state, which also have an influence to their physiological activity, systematic crystallization experiments were performed and as a result, X-ray quality single crystals were obtained from four succinobucol-sterol conjugates. All of these compounds crystallized in space group P1 with two or four moleculesin an asymmetric unit and the crystallographically independent molecules were found to be related by pseudosymmetry (i.e. by pseudoinversion in 1-3 and by pseudoinversion plus pseudotranslation in 4).
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)