Crystallization, Spectral, Crystallographical, and Thermoanalytical Studies of Succinobucol Polymorphism

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F12%3A43894020" target="_blank" >RIV/60461373:22330/12:43894020 - isvavai.cz</a>

Alternative codes found

RIV/61389030:_____/12:00380695

Result on the web

<a href="http://dx.doi.org/10.1002/jps.23068" target="_blank" >http://dx.doi.org/10.1002/jps.23068</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/jps.23068" target="_blank" >10.1002/jps.23068</a>

Result language

angličtina

Original language name

Crystallization, Spectral, Crystallographical, and Thermoanalytical Studies of Succinobucol Polymorphism

Original language description

Four different polymorphs, A, C, D, and E, of succinobucol were isolated and characterized by means of solid-state nuclear magnetic resonance spectroscopy, single crystal and powder X-ray diffraction, differential scanning calorimetry, thermogravimetry,and attenuated total reflection-infrared spectroscopy. From a number of experiments, the same polymorphs (C, D, and E) and an equilibrium phase mixture B consisting of polymorphs C and D were repeatedly gained using different solvents or their mixtures.Although polymorph A was obtained directly from recrystallization only on few occasions, polymorphs C, D, and E proved to be metastable kinetic polymorphs, which slowly transform to a thermodynamically more stable form A during long-term storage. The single-crystal structures of polymorph C and D were determined by X-ray single-crystal diffraction.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CC - Organic chemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal Pharm.Science

ISSN

0022-3549

e-ISSN

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Volume of the periodical

101

Issue of the periodical within the volume

5

Country of publishing house

US - UNITED STATES

Number of pages

9

Pages from-to

1794-1802

UT code for WoS article

000302800100015

EID of the result in the Scopus database

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